Penile Botox on Harley Street — 10,000+ Procedures, World-Class ED Treatment

When a consultant plastic surgeon with over 10,000 penile procedures tells you there is a better approach to ED than daily pills, it is worth listening. Dr. Gary Horn, operating from 64 Harley Street, performs UroFirm™ penile Botox.

£800 Per Treatment Harley Street 20-Minute Procedure No Downtime
100 Units
Botulinum Toxin
15-25 Min
Procedure Time
~6 Months
Duration of Results
£800
All-Inclusive Price

When a consultant plastic surgeon with over 10,000 penile procedures tells you there is a better approach to ED than daily pills, it is worth listening. Dr. Gary Horn, operating from 64 Harley Street, performs UroFirm™ penile Botox — an intracavernosal injection of botulinum toxin that relaxes the smooth muscle restricting blood flow in the erectile tissue. The result is firmer, more spontaneous erections over the following months. No Viagra. No Cialis. No daily medication. For men across the UK, Europe, and internationally, this is ED treatment at the apex of provider experience and clinical credentialing.

The Science

The corpus cavernosum — the two chambers of erectile tissue — must fill with blood under arterial pressure to produce an erection. Smooth muscle relaxation gates this process. Norepinephrine contracts the muscle. In ED, contractile tone is excessive, limiting inflow.

UroFirm™ delivers 100 units of botulinum toxin into the corpus cavernosum via intracavernosal injection. The toxin blocks norepinephrine release at the neuromuscular junction. Smooth muscle tone decreases. Arterial blood flow into the chambers increases. Randomised controlled trials confirm the mechanism: improved peak systolic velocity on Doppler, improved SHIM and IIEF scores.

Topical numbing cream. Quick injection. No downtime. Initial results in one to two weeks. Peak effect at four to six weeks. Duration: approximately six months.

1

Numbing Cream Applied

A topical anesthetic is applied to the treatment area. You relax for about 15 minutes while it takes full effect, ensuring your comfort throughout the procedure.

2

Botulinum Toxin Injected

Your provider injects 100 units directly into the corpus cavernosum. The injection itself takes just a few minutes. Most men describe only a brief pinch or pressure.

3

Results Develop

You leave the office and go about your day — no downtime. Improvement begins within one to two weeks, with full results at four to six weeks lasting approximately six months.

What This Treatment Delivers

Firmer, more spontaneous erections. Reduced dependence on pharmaceutical ED treatment. Enhanced response to PDE5 inhibitors for men who continue them. Reduced retraction — a fuller resting state. Restored sexual confidence. Published clinical trial support. And the assurance that the world’s most experienced penile procedure specialist is performing your treatment — there is no more credentialed provider for this procedure.

Firmer Erections

Firmer, more spontaneous erections. Reduced dependence on pharmaceutical ED treatment.

Enhanced Medication Response

Enhanced response to PDE5 inhibitors for men who continue them. Many men reduce or stop medication altogether.

Less Retraction

Reduced retraction — a fuller resting state. Restored sexual confidence.

World-Class Provider

Published clinical trial support. The world’s most experienced penile procedure specialist performing your treatment — there is no more credentialed provider.

Candidates

Men across the UK and internationally experiencing declining erection quality. Men who want the most experienced provider available. Men who want an evidence-based alternative to lifelong medication. Men who expect Harley Street standards.

✓ Ideal Candidates

  • Men across the UK and internationally experiencing declining erection quality
  • Men who want the most experienced provider available
  • Men who want an evidence-based alternative to lifelong medication
  • Men who expect Harley Street standards

✗ This May Not Be Right If…

  • You have a known allergy to botulinum toxin products
  • You have an active infection at the injection site
  • You are looking for a permanent, one-time solution
  • You have untreated severe underlying vascular conditions

Your Appointment

Arrive at Androfill Clinic, 64 Harley Street

You check in and are brought to a private treatment room. Your provider reviews the procedure and answers any final questions.

Numbing Cream Applied

A topical numbing cream is applied to the penis. You relax for roughly 15 minutes while it takes full effect.

Injection Performed

100 units of botulinum toxin injected into the corpus cavernosum. The injection itself takes just a few minutes.

Walk Out & Resume Your Day

Under 25 minutes total. No restrictions, no recovery period. You leave and go about your day.

Results Develop Over 1–6 Weeks

Improvement begins within one to two weeks. Full effect at four to six weeks, lasting approximately six months.

One Treatment. One Price.

£800
Per Treatment — All-Inclusive
  • 100 units of botulinum toxin (neuromodulator)
  • Complete in-office procedure
  • Follow-up consultation included
  • No hidden fees — cash-pay, not billed through insurance
  • Financing available through PayItMonthly
ED medications typically cost £20–£50/month (£240–£600/year) — plus the hassle of daily planning. UroFirm™ delivers months of improved erectile function from a single 20-minute appointment.
Book Your Harley Street Consultation

Your London Provider

Dr. Gary Horn, MD — Urosculpt Provider
★ Master Certified

Dr. Gary Horn, MD

Dr. Gary Horn is a consultant plastic and reconstructive surgeon, uro-andrologist, and Urosculpt™ Master Certified provider with over 10,000 penile procedures performed across 25+ years. Founder of Androfill Clinic on Harley Street. Featured in BBC documentaries. Practices in London, Paris, and Brussels.

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Clinic Location

64 Harley Street, London W1G 7HB

Get Directions +44 7426 040 086

What Our Patients Say

Frequently Asked Questions

Botulinum toxin injected into the corpus cavernosum blocks norepinephrine release, relaxing smooth muscle and improving arterial blood flow into the erectile chambers. The result is measurably firmer erections, confirmed by Doppler studies.
In the hands of a provider with over 10,000 penile procedures, the safety profile is exceptional. Published randomised controlled trials show improved erectile function with minimal adverse events. The procedure is off-label but supported by strong clinical evidence.
Topical numbing cream is applied beforehand. The injection itself is a brief sensation — most patients describe it as very tolerable.
Three to six months. Repeat treatments every four to six months maintain the benefit.
Initial improvement within one to two weeks. Full effect at approximately four to six weeks.
Yes. UroFirm™ works through a completely different pathway. Many men report dramatically improved medication response after treatment. Some reduce or stop medication altogether.
Entirely different treatments. UroFirm™ (Botox) improves erectile function and blood flow. Penile filler (Urosculpt™/Upsize™) adds physical girth. Many men at Androfill combine both — filler for size, Botox for performance.
Botulinum toxin is approved by regulatory bodies worldwide (FDA in the US, MHRA in the UK) for numerous indications. Intracavernosal injection for ED is an off-label application, supported by published clinical evidence and specialist physician judgment.

Serving London & International Patients

Androfill Clinic on Harley Street serves men across London, the Home Counties, Southeast England, and internationally — with patients regularly travelling from across the UK, Europe, and the Middle East. Located at 64 Harley Street, W1G 7HB.

London Home Counties Southeast England UK Europe Middle East International

Published Research

  1. El-Shaer W, et al. “Intracavernosal injection of botulinum toxin type A for treatment of vasculogenic erectile dysfunction: a prospective, randomized, double-blind, placebo-controlled study.” Andrology. 2021;9(4):1166–1174. doi:10.1111/andr.13005
  2. Elshamma NO, et al. “Safety and efficacy of intracorporal injection of botulinum toxin type A in management of vascular erectile dysfunction in diabetic patients.” Andrologia. 2022;54(5):e14399. doi:10.1111/and.14399
  3. Mehta P, et al. “Botulinum toxin A injection into the corpus cavernosum for erectile dysfunction: systematic review and meta-analysis.” Sexual Medicine Reviews. 2023;11(3):238–247. doi:10.1093/sxmrev/qead020
  4. Giuliano F, et al. “The role of botulinum toxin in neuro-urology: clinical implications.” European Urology. 2022;82(1):1–10.

Book Your Harley Street Consultation

Fill out the form below and the Androfill Clinic team will contact you to schedule your consultation at 64 Harley Street.

📍 64 Harley Street, London W1G 7HB